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Search Results for " t. gondii "

11

Compounds

Cat No. Product Name Synonyms Targets
T7943 Fluphenazine decanoate Dopamine Receptor
Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.
T72081 CpCDPK1/TgCDPK1-IN-2 Parasite
CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can be used in the study of diseases associated with infection of...
T36692 Fanotaprim DHFR
Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM and a hDHFR IC50 of 308 ± 71 nM and a hDHFR to TgDHFR selectivity ratio o...
T21687 Conoidin A Parasite
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation ...
T61671 MMV687807
MMV687807 is a potent anthelmintic compound exhibiting strong efficacy against Toxoplasma gondii (T. gondii). It demonstrates an IC50 value of 0.15 μM and a CC50 value of 1.69 μM [1].
T11846 LHVS Cysteine Protease
LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine protease inhibitor.
T40191 17-GMB-APA-GA
17-GMB-APA-GA, a potent HSP90 inhibitor, is an ADC cytotoxin commonly employed for studying latent T. gondii infection.
T61114 Anti-Trypanosoma cruzi agent-2
Anti-Trypanosoma cruzi agent-1 (Compd 3b), selective compound against NINOA trypomastigote (IC 50 = 0.51 μM) and INC-5 epimastigote form (IC 50 = 3.06 μM), posseses anti- T. gondii activity [1].
T83881 4-(3,4-Difluorobenzo)curcumin CDF
4-(3,4-Difluorobenzo)curcumin (CDF) is a semisynthetic coumarin noted for its antiparasitic and anticancer properties. It effectively reduces the population of Vero cells infected by T. gondii promastigotes and amastigot...
T17257 WR99210 DHFR , Antifolate , Antibacterial
WR99210 is a potent, orally available and less toxic dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 has good antiparasitic activity against P. vivax and P. falciparum strains (including P. falciparum s...
T35750 Trypacidin
Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, re...
TargetMol